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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC1A6 All Species: 23.64
Human Site: S523 Identified Species: 65
UniProt: P48664 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48664 NP_005062.1 564 61565 S523 A A V I E H L S Q R E L E L Q
Chimpanzee Pan troglodytes XP_001146398 542 59526 S498 A G I V E H L S R H E L K N R
Rhesus Macaque Macaca mulatta XP_001094417 542 59560 S498 A G I V E H L S R H E L K N R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O35544 561 60766 S520 A A V I E H L S Q R E L E L Q
Rat Rattus norvegicus O35921 561 60697 S520 A A V I E H L S Q R E L E L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418178 546 59898 D503 I A V D W F L D R L R T T T N
Frog Xenopus laevis NP_001083306 542 59629 S498 A G I V E H L S R H E L K G G
Zebra Danio Brachydanio rerio NP_001103173 560 60844 S518 A G I V E H L S R Q E L Q N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10901 503 54657 D463 V Y H Y S K A D L D A H D R L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.9 66.1 N.A. N.A. 95.2 94.6 N.A. N.A. 72.8 65 65.2 N.A. N.A. N.A. 44.3 N.A.
Protein Similarity: 100 81.3 81.5 N.A. N.A. 96.9 96.6 N.A. N.A. 84.4 80.8 80.1 N.A. N.A. N.A. 63.1 N.A.
P-Site Identity: 100 46.6 46.6 N.A. N.A. 100 100 N.A. N.A. 20 46.6 53.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 80 80 N.A. N.A. 100 100 N.A. N.A. 26.6 73.3 86.6 N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 78 45 0 0 0 0 12 0 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 23 0 12 0 0 12 0 0 % D
% Glu: 0 0 0 0 78 0 0 0 0 0 78 0 34 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 45 0 0 0 0 0 0 0 0 0 0 0 12 12 % G
% His: 0 0 12 0 0 78 0 0 0 34 0 12 0 0 0 % H
% Ile: 12 0 45 34 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 12 0 0 0 0 0 0 34 0 0 % K
% Leu: 0 0 0 0 0 0 89 0 12 12 0 78 0 34 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 12 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 34 12 0 0 12 0 45 % Q
% Arg: 0 0 0 0 0 0 0 0 56 34 12 0 0 12 23 % R
% Ser: 0 0 0 0 12 0 0 78 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 12 12 12 0 % T
% Val: 12 0 45 45 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _